Scientific Research

1. Roles of three-dimensional transcriptional regulation of lncRNAs and 3D genome structure in brain aging.

2. Transcriptional regulation of lncRNAs and higher order chromatin structures in spermatogenesis.

• piR-36249 and DHX36 together inhibit testicular cancer cells progression by upregulating OAS2..Noncoding RNA Research,2023,8(2):174-186.
• Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress..iScience,2022,26(1):
• The landscape of aging..Science China. Life sciences,65(12):2354-2454.
• Stub1 maintains proteostasis of master transcription factors in embryonic stem cells..Cell Reports,2022,39(10):
• NicE-C efficiently reveals open chromatin-associated chromosome interactions at high resolution..Genome Research,32(3):534-544.
• The long noncoding RNA Synage regulates synapse stability and neuronal function in the cerebellum..Cell Death & Differentiation,28(9):2634-2650.